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Endometrial Biopsy

Like in other biopsies, a tissue sample is obtained from the endometrium (the inside lining of the uterus) and is then observed under a microscope

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Endometrial Biopsy

A procedure in which a tissue sample is obtained from the endometrium (the inside lining of the uterus) and is then observed under a microscope...Read More

Posted on : Thursday, February 5, 2009 12:00 AM
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I just had my endometrial biopsy 20 minutes ago. I was very surprised how unpainful it was. I was very scarred and nervous and I wanted to back out of my appointment several times. I usually faint during medical proceedures but fortunately not with the endometrial biopsy. I took Misoprostol ( cervix dialation ) the night before. I also took 2 tablets of Ibuprofen pm the night before to be able to sleep. In the morning I took 4 tablets of 200 mg ibuprofen at 7 am. Then I took 1 tablet of percocet ( prescription painkiller that I had from my c- sections) and I took another 4 tablets of Ibuprofen 200 mg at noon. I took 2 more Ibuprofen 200 mg at 1:00 pm and 2 more percocet. That must have done the trick as I felt almost nothing. She used the clamps to hold the cervix and that felt like a little pinch nothing unbearable. Then she used what looked like big long cottonswaps to collect the sample. She said the cervix is plenty dialated due to the Misoprostol so that helped a lot. I felt a little swaping when she collected the samples but no pain. I felt a little pinch when she took the clamps off. That was it. When she entered the uterus with the cotton swaps she made me cough all the way so that I would not feel anything. I am very reliefed. Now I feel a little bit of cramping sitting at my desk but nothing real painful. So make sure the Dr. Office will give you a prescription for the Misoprostol 100 and a prescription painkiller as the ibuprofen alone might not have prevented any pain. It is not as bad as it sounds on the websites so head up you can do it!
Replied on Friday, May 11, 2012 2:45 PM

I had an endometrial biopsy about three months ago, straight after having my merina coil removed. I almost passed out with the pain and it felt like my insides had been cut out. I'm 55, not a sissy and have had three kids naturally. I couldn't have driven myself home I felt so dreadful. I had another appointment at the NHS clinic yesterday and explained that all my symptoms had settled and wasn't prepared to go through another procedure. The department head then came and told me that due to the results from the last biopsy I would have to have the procedure again to rule out cancer. Obviously I can't argue with that but am now absolutely terrified to go back and get it done. I can't believe that in this day and age anyone should have to suffer that sort of pain. I wasn't offered any sort of pain relief, no-one mentioned the Misoprostol [anyone know where I could get some in the UK?] Any advice greatly appreciated.
Replied on Thursday, May 17, 2012 8:45 AM
I had my biopsy done 2 days ago. You definitely need someone to drive you home after the procedure. I'm very sensitive to medications. I thought taking 500mg of Tylenol was enough for me since it usually knocks me out to the next day. But after the procedure was over...the tears were rolling down my cheeks and I took another 500mg of Tylenol right away as I rested on the table. It so painful. I felt so numb from the hip down to my feet! I'm 45 and had 3 children. It was still very painful!
Replied on Friday, June 29, 2012 7:21 PM

I just had an EMB done today. I read all over the internet about the horrible pain there would be and I really was scared. Before the procedure, I took 800mg of ibuprofen just in case. It took my doctor literally 3 min to get 2 biopsies. There was a little cramping and discomfort as she inserted the tube twice but I honestly never felt the suction of my tissue from the tube. That was it. Actually, i felt more pain during my colposcopy earlier this year[still not extreme]. I felt fine enough afterward to walk and drive home. Dont get worked up for nothing, SERIOUSLY!! Take some ibuprofen before and just take deep breaths. You will be fine. Good luck!
Replied on Tuesday, August 14, 2012 10:48 AM
I had my biopsy yesterday. It was unexpected so I could not prepare for the pain. It hurt like hell! It felt like a large sharp object was poking around and slashing the inside of my uterus. I was yelling! Loudly. She kept apologizing. She got her first sample but felt like there wasn't enough tissue so had go in again!!!! I made her wait though, trying to get the pain to subside. It didn't. Then more searing, agonizing pain! I was sweating. Afterwards, I lay on the table, panting, waiting for the pain to go away. It ebbed but I had cramps all night. If I have to have this done again, I will definitely take some pain meds and a muscle relaxer.
Replied on Saturday, September 22, 2012 10:46 AM

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