Hi!
I just had my endometrial biopsy 20 minutes ago. I was very surprised how unpainful it was. I was very scarred and nervous and I wanted to back out of my appointment several times. I usually faint during medical proceedures but fortunately not with the endometrial biopsy. I took Misoprostol ( cervix dialation ) the night before. I also took 2 tablets of Ibuprofen pm the night before to be able to sleep. In the morning I took 4 tablets of 200 mg ibuprofen at 7 am. Then I took 1 tablet of percocet ( prescription painkiller that I had from my c- sections) and I took another 4 tablets of Ibuprofen 200 mg at noon. I took 2 more Ibuprofen 200 mg at 1:00 pm and 2 more percocet. That must have done the trick as I felt almost nothing. She used the clamps to hold the cervix and that felt like a little pinch nothing unbearable. Then she used what looked like big long cottonswaps to collect the sample. She said the cervix is plenty dialated due to the Misoprostol so that helped a lot. I felt a little swaping when she collected the samples but no pain. I felt a little pinch when she took the clamps off. That was it. When she entered the uterus with the cotton swaps she made me cough all the way so that I would not feel anything. I am very reliefed. Now I feel a little bit of cramping sitting at my desk but nothing real painful. So make sure the Dr. Office will give you a prescription for the Misoprostol 100 and a prescription painkiller as the ibuprofen alone might not have prevented any pain. It is not as bad as it sounds on the websites so head up you can do it!