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Lyme diseaseis a tick-borne disease is caused by the Borrelia burgdorferi bacteria. Ticks carry the bacteria from deer and mice to humans, and the disease is more common in heavily wooded areas. The disease first manifests with a characteristic bull-eye shaped skin rash and fever, and if untreated can affect the heart, joints, and nervous system.Join our online support group for people with Lyme disease and their families. Ask your questions to experts and share your experiences.