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risk factors for colon cancer

Posted by aranganathan on Mon, 07 Mar 2011         
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Risk factors for colon cancerAge: Colorectal cancer  is more common in people over the age of 50 and the chance of developing colorectal cancer increases as age increases. More than 90% of people who develop colorectal cancer are older than 50 years.Diet: The development of colorectal cancer appears to be associated with diet that contains high amount of fat and calories and subsequently low in fiber. High intake of meat may be associated with colorectal cancer. The exact role of dietary factors... Read More
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Risk factors |  Age |  diet |  polyps | 

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HNPCC is also known as Lynch Syndrome. Lynch syndrome is caused by a defective mismatch repair gene which ordinarily corrects defects occurring during DNA replication. As a result, errors continue to mount and tumors and cancers are likely to develop, often at a young age. Children of individuals with LS face a 50% chance of acquiring the gene. Over 600,000 persons in the United States are projected to be affected by LS however less than five percent have been diagnosed. Vulnerable, the rest often contract cancer which is often not detected until the later stages of development when survivability is uncertain, as the dwell time for Lynch syndrome cancers is one to three years, compared with the often five to ten years for sporadic cancers. Lifetime risks of cancer for those with LS include an up to 85% of contracting colon cancer, a 65-70% for endometrial cancer and a higher than average chance of developing cancer of the gastric tract, ovaries, liver, gallbladder duct, pancreas, ureters, bladder, kidneys, prostate, skin and the brain. Currently, there is no cure, but hope exists through genetic testing. Diagnosis of Lynch syndrome begins with individuals learning their family history of cancer. Upon assessment, the physician will determine whether or not to refer an individual to a genetic counselor for further assessment or to immediately prescribe genetic testing (a simple blood test or saliva swab.) If positive, individuals are screened for cancers on an annual basis. Polyps and tumors are detected and removed or treated before reaching a life threatening stage. As a result, people may live longer than previous generations due to early detection and preventative measures. To learn more about Lynch syndrome, please visit www.lynchcancers.com, sponsored by Lynch Syndrome International, a nonprofit, all volunteer organization, dedicated toward Lynch syndrome support, education, research endeavors and public awareness.

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