I am a graduate student currently working on the Pharmacokinetic parameters of oral amodiaquine in Ghanaians. It has been observed and established that there is a significant difference between the study subjects of Ghanaians and Zambian adults as far as the disposition or pharmacokinetics of amodiaquine is concerned. This implies that there might be the need for separate dosing regimen of the drug among the two sub populations. For an optimization of the therapeutic use of the drug in Ghana, there is the urgent need for its dosing regimen adjustment; since there is the speculation that the dosing regimen of amodiaquine in the West African sub region,(hence Ghana) is based on pharmacokinetic studies on East African subjects. The grapevine source of this vital information has been my bone of contention and I would be most grateful if the source could be made available to me. The availability of the original source of this information may go a long way to assist in developing a more appropriate dosing regimen of the drug in this part of a malaria-proned world, (West African sub region).
Looking forward for a favourable response soon. Thank you.

Ango Bediako