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Yeast Genetics Offers Potential Drug Target For Lou Gehrig's Disease
medindia 8870 Posts Lou Gehrig''s disease or Amyotrophic lateral sclerosis, is a devastatingly cruel neurodegenerative disorder that robs sufferers of the ability to move, speak and finally breathe. Read More
Posted on : Wednesday, November 28, 2012 1:15 PM

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sadako12

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My one question about this is the activity after TDP-43 binds to the lariats? Does it act as Dbr1 does and degrade the lariat? Otherwise, I would think TDP-43 would still form clumps, except the clumps this time would include the lariat structure.

Replied on Wednesday, November 28, 2012 1:15 PM

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