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Back pain affects eight in ten people at some point in their lives – it can be a dull ache or sharp shooting pain any part of the back, and it can be caused by nerve or muscle problems, arthritis, or degenerative disc disease.Join our online support group for back pain to get more information about the condition and meet doctors and others professionals who can help.
Cyclobenzaprine hcl has the most recent and largest clinical trials demonstrating its benefit, but , diazepam and metaxalone also appear to be effective. In an attempt to determine the mechanism of action of carisoprodol in the treatment of low back pain, was carried out comparing its effectiveness to that of a sedative medication butabarbital, and a placebo. Carisoprodol was significantly more effective in providing both pain relief and improvements in range of motion. In addition to the skeletal muscle-relaxing effects, carisoprodol also produces weak anticholinergic, antipyretic, and analgesic effects. Cyclobenzaprine and carisoprodol were compared in the treatment of patients with acute thoracolumbar pain and spasm rated moderate to severe and of no longer than seven days duration. Both drugs were effective, without significant differences between the treatment groups. Significant improvements were noted in physician rated mobility and in patients' visual analogue scores on follow up days four and eight.
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