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Fubar Drunk Dating Try to understand your depression. Depression affects people both physically and psychologically. If you stay anxious or stressed for a time period, your brain may slow down on serotonin production. This chemical imbalance may enhance your overall feeling of depression. A doctor may prescribe antidepressants as part of your treatment plan; many of these medications work by stimulating your brain to produce more serotonin. There are natural ways to help increase your serotoni