Since my cardiologist gave me a CT scan of the heart which showed I had 45 to 50% blockages in most of the arteries, my primary physician said I should try Crestor. I don't smoke, have maybe 25 extra pounds, but because of a family history of heart desease (parents dead by the time I was 22)I'm clogged up like a can of crisco. But since women are underdiagnosed on heart desease and I'm only 52, I figure I'll be proactive and give this stuff a try. I'll let you know.