I agree with the conclusion of the article but not with the reason given for it. The article fails to mention that there are significant safety issues associated with this drug, due to its toxicity. It is e.g. responsible for by far the greatest number of therapeutic poisonings in children. Lowering a fever is in any case dangerous as fever plays an important role in dealing with infections. "...evidence suggests that aspirin and paracetamol [the generic name for acetaminophen] increase mortality in severe infection, and that they may prolong the infection and reduce the antibody response in mild disease." Aust Prescr 1995; 18: 233-234, Frank Shann, Intensive Care Unit, Royal Children's Hospital, Melbourne Giving this drug following the administration of vaccines is doubly dangerous as vaccines and acetaminophen may both impair liver function.