There is no cure for cold sores. But medications may slightly reduce the duration of outbreak and sometimes prevent a future outbreak.



Cold sores are best treated as early as possible. Starting treatment when prodromal symptoms (burning, tingling, or redness) begin gives the best chance of keeping the cold sores from developing.



Antiviral medications can:

- Decrease the time it takes for cold sores to heal

- Reduce symptoms - especially pain

- Prevent lesions from occurring if taken soon enough

- Reduce the number of lesions developed if taken soon enough

- Reduce viral shedding



Topical acyclovir can reduce pain, itching, and healing time. Oral


Valacyclovir if started at the first sign of symptoms (2 gm twice a day for one day) may shorten the herpes infection by a little over one day.



Vitamin C, Lysine, and lemon balm may provide some relief during a cold sore outbreak. Zinc oinment may be also very effective remedy.